Trade name： Giotrif

Therap-Cat: Anticancer

Originator: Boehringer Ingelheim

Indication：the first-line treatment of patients with distinct types of metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC)

Chemical name：N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4(dimethylamino)-2-butenamide

CAS#: 850140-72-6

Chemical structure:

Intermediates of Afatinib: