Tedizolid Phosphate（formerly torezolid）

Trade name: Sivextro

Sponsor: CUBIST PHARMACEUTICALS

Therop-Cat: an oxazolidinone-class antibiotic

Indication: acute bacterial skin and skin structure infections (ABSSSI)

Chemical name: [(5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate

CAS# 856867-55-5

Chemical structure:

Tedizolid

CAS#856866-72-3

Chemical name: (R)-3-(3-fluoro-4-(6-(2-Methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxyMethyl)oxazolidin-2-one

Chemical structure:

Intermediates of Tedizolid

1. CAS#444335-16-4 : (5R)-3-(4-broMo-3-fluorophenyl)-5-(hydroxyMethyl)-1,3-oxazolidin-2-one

Chemical structure:

    2. CAS#1056039-83-8 : 2-(2-Methyl-2H-tetrazol-5-yl)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine

Chemical structure: